Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886944 | 0.82 | MAPT (0.89) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11284789 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9621677 | 0.80 | MAPT (0.67) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30818066 | 0.80 | MAPT (1.00) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2762916 | 0.80 | ALDH1A1 (0.64) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11285727 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL874739 | 0.77 | RAB9A (0.71) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10985021 | 0.77 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1304933 | 0.76 | MAPT (0.78) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9426427 | 0.75 | SRD5A2 (0.53) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |