Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874528 | 0.84 | RAB9A (0.72) | RAB9AGAAMGAMSIMGAM2 | |
| SCHEMBL8867718 | 0.83 | RAB9A (1.00) | RAB9AGAASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27479142 | 0.83 | CCNA2 (0.55) | RAB9AGAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL27996903 | 0.78 | KDM4E (0.49) | RAB9AGAASMN1; SMN2MAPTAPP | |
| SCHEMBL11280392 | 0.77 | MAPT (0.67) | RAB9AGAAMGAMSIMGAM2 | |
| SCHEMBL874463 | 0.77 | RAB9A (0.65) | RAB9AGAAMGAMSIMGAM2 | |
| SCHEMBL874800 | 0.77 | RAB9A (0.62) | RAB9AGAAMGAMSIMGAM2 | |
| SCHEMBL5192459 | 0.77 | PTGDR2 (0.53) | RAB9AGAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL874100 | 0.76 | RAB9A (0.64) | RAB9AGAASMN1; SMN2MAPTMEN1 | |
| SCHEMBL874904 | 0.74 | RAB9A (0.58) | RAB9AGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |