Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126898 | 0.87 | TRPV1 (0.41) | MALT1MAPTALDH1A1TP53KIT | |
| SCHEMBL1126371 | 0.81 | MAPT (0.39) | NPY2RMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1126932 | 0.78 | MAPT (0.38) | MALT1MAPTALDH1A1KITPDGFRA | |
| SCHEMBL1127445 | 0.78 | TRPV1 (0.39) | MALT1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1126527 | 0.77 | MAPT (0.37) | MAPTALDH1A1LMNA | |
| SCHEMBL1127448 | 0.76 | ALDH1A1 (0.39) | NPY2RMALT1MAPTALDH1A1KMT2A | |
| SCHEMBL1127042 | 0.76 | POLB (0.45) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL30234914 | 0.76 | POLB (0.45) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL1127185 | 0.75 | MALT1 (0.37) | NPY2RMALT1MAPTALDH1A1KMT2A | |
| SCHEMBL1127265 | 0.75 | KDR (0.37) | MALT1MAPTALDH1A1KMT2AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |