Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126527 | 0.92 | MAPT (0.37) | MAPTALDH1A1USP2HSD17B10POLB | |
| SCHEMBL1126932 | 0.90 | MAPT (0.38) | MALT1MAPTALDH1A1USP2HSD17B10 | |
| SCHEMBL1127445 | 0.88 | TRPV1 (0.39) | MALT1MAPTALDH1A1USP2HSD17B10 | |
| SCHEMBL1126898 | 0.86 | TRPV1 (0.41) | MALT1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL1127265 | 0.86 | KDR (0.37) | MALT1MAPTALDH1A1USP2HSD17B10 | |
| SCHEMBL1127332 | 0.85 | MCHR1 (0.39) | MALT1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL1127076 | 0.84 | TRPV1 (0.38) | MALT1MAPTALDH1A1USP2NPY2R | |
| SCHEMBL1127448 | 0.83 | ALDH1A1 (0.39) | MALT1MAPTALDH1A1USP2NPY2R | |
| SCHEMBL1993703 | 0.83 | LMNA (0.37) | MALT1MAPTALDH1A1USP2NPY2R | |
| SCHEMBL1991279 | 0.82 | DRD4 (0.39) | MAPTALDH1A1NPY2RHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |