Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CDH1 | P12830 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279312 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2CDH1CTNNB1TCF7L2THRB | |
| SCHEMBL11274781 | 0.87 | TRPV1 (0.42) | SMN1; SMN2RAB9ANPC1NOTUMMAPT | |
| SCHEMBL11285150 | 0.76 | RAB9A (0.64) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL11282455 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2CDH1CTNNB1TCF7L2TP53 | |
| SCHEMBL6027661 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2CDH1CTNNB1TCF7L2RAB9A | |
| SCHEMBL11279357 | 0.68 | RAB9A (0.61) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL11299628 | 0.68 | RAB9A (0.64) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL11276082 | 0.68 | RAB9A (0.60) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL10870497 | 0.68 | SMN1; SMN2 (0.57) | SMN1; SMN2CDH1CTNNB1TCF7L2RAB9A | |
| SCHEMBL11294081 | 0.68 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | claimed |
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0048162-A1 | Isoxazolylbenzamides | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |