Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CDH1 | P12830 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870497 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2CDH1CTNNB1TCF7L2NOTUM | |
| SCHEMBL10867981 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CDH1CTNNB1TCF7L2NOTUM | |
| SCHEMBL2840069 | 0.73 | KMO (0.54) | SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9550201 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CDH1CTNNB1TCF7L2NOTUM | |
| SCHEMBL6027499 | 0.72 | CTRC (0.43) | SMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL892967 | 0.71 | CDH1 (0.82) | SMN1; SMN2CDH1CTNNB1TCF7L2NOTUM | |
| SCHEMBL28762616 | 0.70 | NOTUM (0.43) | SMN1; SMN2NOTUMNPC1RAB9ATP53 | |
| SCHEMBL30316029 | 0.70 | ALDH1A1 (0.48) | SMN1; SMN2NOTUMNPC1RAB9ATP53 | |
| SCHEMBL11279312 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2CDH1CTNNB1TCF7L2THRB | |
| SCHEMBL1686347 | 0.69 | POLB (0.66) | SMN1; SMN2CDH1CTNNB1TCF7L2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |