Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.52 |
| ▸ | PREP | P48147 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600176 | 0.83 | FKBP1A (0.41) | FKBP1AACE | |
| Hydrochloric Acid SCHEMBL7263625 | 0.83 | FKBP1A (0.56) | FKBP1APREPALDH1A1CYP3A4TSHR | |
| SCHEMBL6788131 | 0.81 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL6788139 | 0.81 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL11940447 | 0.81 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL11274848 | 0.81 | CTRB1 (0.52) | ACE | |
| SCHEMBL10794593 | 0.80 | ACE (0.59) | ACE | |
| SCHEMBL10794601 | 0.80 | ACE (0.59) | ACE | |
| SCHEMBL11281963 | 0.79 | CTRB1 (0.47) | PREPACETSHR | |
| SCHEMBL11281958 | 0.79 | CTRB1 (0.47) | PREPACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007477-B1 | 1-(3-MERCAPTO-2-METHYLPROPANOYL)PROLYL AMINO ACID DERIVATIVES AND SALTS THEREOF, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | Dainippon Pharmaceutical Co., Ltd. (JP) | 1982-04-28 | — | — | EP | disclosed |
| US-4248883-A | ANTIHYPERTENSION AGENTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1981-02-03 | — | — | US | disclosed |
| EP-0007477-A1 | 1-(3-Mercapto-2-methylpropanoyl)prolyl amino acid derivatives and salts thereof, processes for their preparation, and pharmaceutical compositions containing such compounds | Dainippon Pharmaceutical Co., Ltd. (JP) | 1980-02-06 | — | — | EP | disclosed |