Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 12/20 | 0.64 |
| ▸ | PREP | P48147 | 3/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788139 | 0.93 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL6788131 | 0.93 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL18806512 | 0.90 | FKBP1A (0.61) | FKBP1APREPACE | |
| SCHEMBL10343310 | 0.90 | FKBP1A (0.61) | FKBP1APREPACE | |
| SCHEMBL6787826 | 0.89 | FKBP1A (0.60) | FKBP1APREPACE | |
| SCHEMBL6787817 | 0.89 | FKBP1A (0.60) | FKBP1APREPACE | |
| Hydrochloric Acid SCHEMBL8040977 | 0.89 | FKBP1A (0.60) | FKBP1APREPACE | |
| Hydrochloric Acid SCHEMBL11217224 | 0.89 | FKBP1A (0.60) | FKBP1APREPACE | |
| SCHEMBL23502313 | 0.88 | FKBP1A (0.62) | FKBP1APREPACE | |
| SCHEMBL13018403 | 0.88 | FKBP1A (0.59) | FKBP1APREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2017-05-04 | — | — | US | disclosed |
| US-9243028-B2 | Facile amide formation via S-nitroso thioacid intermediates | WASHINGTON STATE UNIVERSITY (US) | 2016-01-26 | — | — | US | disclosed |
| US-20120190820-A1 | FACILE AMIDE FORMATION VIA S-NITROSO THIOACID INTERMEDIATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
| US-7678765-B2 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A. (ES) | 2010-03-16 | — | — | US | disclosed |
| US-7678765-B2 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A. (ES) | 2010-03-16 | — | — | US | disclosed |
| US-7348310-B2 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A. (ES) | 2008-03-25 | — | — | US | disclosed |
| US-7348310-B2 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A. (ES) | 2008-03-25 | — | — | US | disclosed |
| US-20080009435-A1 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A., A SPAIN CORPORATION | 2008-01-10 | — | — | US | disclosed |
| US-20080009435-A1 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | PHARMA MAR, S.A., A SPAIN CORPORATION | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009435-A1 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them | MCL1, APLNR, PAICS | FKBP1A 3393/4885PREP 635/4885ACE 2441/4885 |
| US-20120190820-A1 | FACILE AMIDE FORMATION VIA S-NITROSO THIOACID INTERMEDIATES | NAAA, TST, ASNS | FKBP1A 2824/4885PREP 674/4885ACE 899/4885 |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, FAH | FKBP1A 589/4885PREP 61/4885ACE 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.