SCHEMBL11280719

SCHEMBL11280719

CSC(C)C1NC(C)(C)CC(C)O1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8008653 0.78 LMNA (0.36) LMNA
SCHEMBL168749 0.68 LMNA (0.43) LMNA
SCHEMBL11281710 0.66 LMNA (0.35) LMNA
SCHEMBL11272195 0.66 LMNA (0.35) LMNA
SCHEMBL13199372 0.62 LMNA (0.46) LMNA
SCHEMBL24006945 0.62
SCHEMBL2818755 0.62 LMNA (0.35) LMNA
SCHEMBL11271781 0.60 LMNA (0.33) LMNA
SCHEMBL11050548 0.59 LMNA (0.36) LMNA
SCHEMBL2818757 0.58 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046451-A2 Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use CIBA-GEIGY AG (CH) 1982-02-24 EP disclosed