SCHEMBL8008653

SCHEMBL8008653

CC1CC(C)(C)NC(C(C)O)O1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11280719 0.78 LMNA (0.34) LMNA
SCHEMBL168749 0.70 LMNA (0.43) LMNA
SCHEMBL11050548 0.65 LMNA (0.36) LMNA
SCHEMBL13199372 0.65 LMNA (0.46) LMNA
SCHEMBL2818755 0.64 LMNA (0.35) LMNA
SCHEMBL5807183 0.63 LMNA (0.37) LMNA
SCHEMBL22856955 0.63
SCHEMBL11281710 0.60 LMNA (0.35) LMNA
SCHEMBL11272195 0.60 LMNA (0.35) LMNA
SCHEMBL11628941 0.59 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720620-B1 GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS TELIK INC (US) 2000-05-24 EP disclosed
US-6013462-A PURIFYING OR ANALYZING A HUMAN GLUTATHIONE-S-TRANSFERASE FROM A SAMPLE BY CONTACTING WITH A SOLID SUPPORT COUPLED TO TRIPEPTIDE ANALOG, AND ALLOWING ENZYME TO ADSORB TO SUPPORT TERRAPIN TECHNOLOGIES, INC. (US) 2000-01-11 US disclosed
US-5786336-A GRANULOCYTE MACROPHAGE PROGENITOR STIMULANTS, TRIPEPTIDES TERRAPIN TECHNOLOGIES, INC. (US) 1998-07-28 US disclosed
US-5763570-A Glutathione analogs and paralog panels comprising glutathione mimics TERRAPIN TECHNOLOGIES, INC. (US) 1998-06-09 US disclosed
US-5599903-A TRIPEPTIDE; LIGAND, ENZYME INHIBITOR TERRAPIN TECHNOLOGIES, INC. (US) 1997-02-04 US disclosed
EP-0720620-A1 GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS TERRAPIN TECHNOLOGIES, INC. (US) 1996-07-10 EP disclosed
WO-1995008563-A1 GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS TERRAPIN TECHNOLOGIES, INC. (US) 1995-03-30 WO disclosed