Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084869 | 0.84 | L3MBTL1 (0.53) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL27381674 | 0.84 | TDP1 (0.53) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL1502428 | 0.84 | TDP1 (0.53) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL4745748 | 0.81 | L3MBTL1 (0.50) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL719034 | 0.79 | NR4A2 (0.85) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL30121738 | 0.79 | NR4A2 (0.85) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL725762 | 0.79 | TRPA1 (0.58) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL9720590 | 0.79 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL21396941 | 0.79 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNANR4A2 | |
| SCHEMBL29165372 | 0.79 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309428-A | Maytansinoids | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |