Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27311002 | 1.00 | TRPA1 (0.58) | TRPA1L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL13220674 | 0.89 | SMN1; SMN2 (0.66) | TRPA1L3MBTL1MAPTLMNAHPGD | |
| SCHEMBL6604832 | 0.88 | L3MBTL1 (0.64) | TRPA1L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL12464189 | 0.86 | TDP1 (0.68) | L3MBTL1MAPTTDP1LMNANR4A2 | |
| SCHEMBL10473788 | 0.86 | CYP3A4 (0.59) | TRPA1L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL1572261 | 0.86 | CYP3A4 (0.59) | TRPA1L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL9181060 | 0.85 | KMT2A (0.55) | TRPA1L3MBTL1MAPTTDP1LMNA | |
| SCHEMBL1122004 | 0.85 | L3MBTL1 (0.71) | L3MBTL1MAPTTDP1LMNANR4A2 | |
| SCHEMBL17867451 | 0.85 | L3MBTL1 (0.71) | L3MBTL1MAPTTDP1LMNANR4A2 | |
| SCHEMBL23782371 | 0.84 | HPGD (0.54) | TRPA1L3MBTL1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114042455-B | Carbonyl selective hydrogenation catalyst and preparation method and application thereof | 浙江新和成股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116023201-B | Preparation method of aromatic alcohol | 浙江新化化工股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117049958-A | Method and reactor for synthesizing ibuprofen from isobutylbenzene | 青岛科技大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116023201-A | Preparation method of aromatic alcohol | 浙江新化化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115487866-A | Covalent organic framework material coupled nano metal catalyst and preparation method thereof | 浙江大学 | 2022-12-20 | — | — | CN | claimed |
| CN-110218201-A | 1,4- benzothiazine and derivative and its synthetic method | 湘潭大学 | 2019-09-10 | — | — | CN | claimed |
| CN-109464412-A | A kind of Nuprin Tablets and preparation method thereof that moisture resistance is high | 安徽东盛友邦制药有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109400518-A | Polysubstituted 6- aryl benzo [a] carbazole and derivative and its synthetic method | 湘潭大学 | 2019-03-01 | — | — | CN | claimed |
| CN-107235990-B | Polysubstituted indoles bithiophene and derivative and its synthetic method | 湘潭大学 | 2019-01-29 | — | — | CN | claimed |
| CN-108997329-A | Polysubstituted 3-(3- benzo [b] selenophen base) -1H-2- (hetero) aryl indole and derivative and its synthetic method | 湘潭大学 | 2018-12-14 | — | — | CN | claimed |
| US-7087791-B2 | Catalysed acylation of alkylated benzene derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL REASEARCH (IN) | 2006-08-08 | — | — | US | claimed |
| EP-1670738-A1 | CATALYSED ACYLATION OF ALKYLATED BENZENE DERIVATIVES | Council of Scientific and Industrial Research (IN) | 2006-06-21 | — | — | EP | claimed |
| US-20050171385-A1 | CATALYSED ACYLATION OF ALKYLATED BENZENE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-08-04 | — | — | US | claimed |
| WO-2005030691-A1 | CATALYSED ACYLATION OF ALKYLATED BENZENE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-07 | — | — | WO | claimed |
| CN-1161441-C | electrostatic aerosol composition | ���ر���˹��(Ӣ��)����˾ | 2004-08-11 | — | — | CN | claimed |
| EP-1409605-A2 | ELECTROSTATIC AEROSOL COMPOSITIONS | Reckitt Benckiser (U.K.) LIMITED (GB) | 2004-04-21 | — | — | EP | claimed |
| US-20030096878-A1 | Electrostatic aerosol compositions | RECKITT BENCKISER (UK) LIMITED | 2003-05-22 | — | — | US | claimed |
| CN-1391599-A | electrostatic aerosol composition | RECKITT BENCKISER UK LTD (GB) | 2003-01-15 | — | — | CN | claimed |
| WO-2001018145-A2 | ELECTROSTATIC AEROSOL COMPOSITIONS | RECKITT BENCKISER (UK) LIMITED (GB) | 2001-03-15 | — | — | WO | claimed |
| EP-0488638-B1 | BF3 catalyzed acetylation of butylbenzene | HOECHST CELANESE CORP (US) | 1997-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171385-A1 | CATALYSED ACYLATION OF ALKYLATED BENZENE DERIVATIVES | MLLT1, ARSA, ENY2 | TRPA1 506/4885L3MBTL1 365/4885MAPT 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.