Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.53 |
| ▸ | RXRA | P19793 | 4/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384222 | 0.82 | PPARD (0.49) | PPARDRXRARXRBALDH1A1KDM4E | |
| SCHEMBL5586019 | 0.82 | PPARD (0.52) | PPARDRXRARXRBKDM4ELMNA | |
| SCHEMBL11279704 | 0.79 | PTGS2 (0.51) | PPARDRXRARXRBKDM4ELMNA | |
| SCHEMBL6539938 | 0.77 | NR4A2 (0.69) | PPARDRXRARXRBALDH1A1KDM4E | |
| SCHEMBL6539369 | 0.77 | ALDH1A1 (0.42) | PPARDALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL3092563 | 0.76 | PPARD (0.53) | PPARDRXRARXRBNR4A2NR4A1 | |
| SCHEMBL9147494 | 0.75 | SIRT2 (0.55) | PPARDRXRARXRBKDM4ELMNA | |
| SCHEMBL31194858 | 0.74 | MAPK13 (0.54) | PPARDALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL6539003 | 0.74 | ALDH1A1 (0.46) | PPARDALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL6539688 | 0.74 | PPARD (0.53) | PPARDRXRARXRBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046451-A2 | Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |