Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 6/20 | 0.46 |
| ▸ | RXRB | P28702 | 6/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 8/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | C5 | P01031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150972 | 0.84 | RXRA (0.43) | SIRT2RXRARXRBNR4A2PPARD | |
| SCHEMBL9152238 | 0.84 | RXRA (0.43) | SIRT2RXRARXRBNR4A2PPARD | |
| SCHEMBL14384222 | 0.83 | PPARD (0.49) | SIRT2RXRARXRBNR4A2PPARD | |
| SCHEMBL4331461 | 0.83 | RXRA (0.71) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9150827 | 0.82 | RXRA (0.55) | SIRT2RXRARXRBNR4A2RXRG | |
| SCHEMBL8113859 | 0.82 | NR4A2 (0.66) | RXRARXRBNR4A2RXRGAOC3 | |
| SCHEMBL4323846 | 0.81 | RXRA (0.53) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL11279704 | 0.81 | PTGS2 (0.51) | RXRARXRBNR4A2PPARDRXRG | |
| SCHEMBL9150003 | 0.80 | RXRA (0.40) | SIRT2RXRARXRBNR4A2PPARD | |
| SCHEMBL4329469 | 0.80 | HDAC1 (0.65) | RXRARXRBNR4A2RXRGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |