Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280949 | 1.00 | NPC1 (0.81) | NPC1L3MBTL1LTB4RLTB4R2HDAC2 | |
| N,N-Diethylcinnamamide SCHEMBL4956221 | 0.90 | NPC1 (1.00) | NPC1L3MBTL1LTB4RLTB4R2HDAC2 | |
| N,N-Diethylcinnamamide SCHEMBL23550023 | 0.90 | NPC1 (1.00) | NPC1L3MBTL1LTB4RLTB4R2HDAC2 | |
| N,N-Diethylcinnamamide SCHEMBL4956226 | 0.90 | NPC1 (1.00) | NPC1L3MBTL1LTB4RLTB4R2HDAC2 | |
| SCHEMBL9590158 | 0.81 | HDAC2 (0.59) | NPC1L3MBTL1LTB4RHDAC2APP | |
| SCHEMBL28501196 | 0.81 | NPC1 (0.72) | NPC1L3MBTL1LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL31228704 | 0.81 | NPC1 (0.72) | NPC1L3MBTL1LTB4RLTB4R2BCHE | |
| SCHEMBL31228779 | 0.81 | NPC1 (0.72) | NPC1L3MBTL1LTB4RLTB4R2BCHE | |
| SCHEMBL7245706 | 0.80 | L3MBTL1 (0.70) | NPC1L3MBTL1LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL9877155 | 0.80 | HDAC2 (0.57) | NPC1L3MBTL1HDAC2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |