Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254423 | 0.91 | LMNA (0.57) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7352169 | 0.84 | NQO1 (0.58) | LMNAMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5254163 | 0.81 | LMNA (0.56) | LMNAALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL5929490 | 0.81 | MAPT (0.62) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8277612 | 0.81 | GAA (0.54) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5258291 | 0.81 | NR5A1 (0.56) | NPC1RAB9A | |
| SCHEMBL15873588 | 0.81 | HRH3 (0.46) | LMNAALDH1A1SMN1; SMN2KDM4EHRH3 | |
| SCHEMBL21052116 | 0.80 | L3MBTL1 (0.53) | ALDH1A1HPGDL3MBTL1KMT2ANPC1 | |
| SCHEMBL17445912 | 0.79 | ALDH1A1 (0.66) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL909956 | 0.78 | LMNA (0.58) | LMNAMAPTALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336191-A | Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |