Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.80 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.80 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187971 | 0.92 | OPRM1 (0.72) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL11712071 | 0.89 | OPRM1 (1.00) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL701023 | 0.89 | OPRM1 (0.63) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL703650 | 0.89 | KDM4E (0.69) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL2789658 | 0.88 | KDM4E (0.61) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| Pheneridine SCHEMBL1922392 | 0.87 | KCNA3 (0.86) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL6746046 | 0.86 | KDM4E (0.60) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL702418 | 0.86 | KDM4E (0.66) | OPRM1OPRD1OPRK1KDM4ENPSR1 | |
| SCHEMBL11599945 | 0.86 | OPRM1 (0.78) | OPRM1OPRD1OPRK1KCNA3SLC22A1 | |
| SCHEMBL11139480 | 0.85 | OPRM1 (0.82) | OPRM1OPRD1OPRK1KCNA3SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329345-A | ANTIARRHYTHMIC AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |