Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914804 | 0.85 | EPHX1 (0.38) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL1837095 | 0.83 | EPHX1 (0.37) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL11612471 | 0.83 | CCR2 (0.38) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL7430651 | 0.83 | EPHX1 (0.37) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL28013415 | 0.83 | MEN1 (0.36) | SMN1; SMN2MAPTEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL27545195 | 0.81 | EPHX1 (0.34) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| Hydrochloric Acid SCHEMBL28148084 | 0.81 | SLC6A3 (0.36) | SMN1; SMN2MAPTEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL20598306 | 0.77 | EPHX1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL21575131 | 0.77 | EPHX1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL4158317 | 0.76 | FDPS (0.35) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321269-A | 1-(3-Halo-1,2-dioxopropyl)-cycloamine compositions and use | SANDOZ, INC. (US) | 1982-03-23 | — | — | US | disclosed |