Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | GRK3 | P35626 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445558 | 0.86 | MEN1 (0.53) | MEN1KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL134016 | 0.86 | EGFR (0.57) | MEN1KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL29613642 | 0.86 | MEN1 (0.53) | MEN1KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL4485291 | 0.85 | PARP14 (0.47) | PARP1PARP10PARP14PARP15MEN1 | |
| SCHEMBL21552480 | 0.85 | MEN1 (0.52) | PARP1PARP10PARP14PARP15MEN1 | |
| SCHEMBL11277128 | 0.82 | AKR1C3 (0.57) | PARP1PARP10PARP14PARP15MEN1 | |
| SCHEMBL18484918 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AAKR1C3ALDH1A1CA12 | |
| SCHEMBL8294937 | 0.80 | MEN1 (0.57) | PARP1PARP10PARP14PARP15MEN1 | |
| SCHEMBL9448456 | 0.80 | PARP1 (0.51) | PARP1PARP10PARP14PARP15MEN1 | |
| SCHEMBL6904254 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009608-B1 | N-PHENETHYLACETAMIDE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-04-21 | — | — | EP | disclosed |
| US-4297357-A | ANTIULCER AGENTS; ANTISECRETORY AGENTS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-10-27 | — | — | US | disclosed |
| EP-0009608-A1 | N-Phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them | DAIICHI SEIYAKU CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |