Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613642 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL134016 | 0.87 | EGFR (0.57) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL11283115 | 0.86 | PARP1 (0.52) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL15057284 | 0.85 | HPGD (0.48) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL28126809 | 0.84 | POLB (0.57) | MEN1KMT2AALDH1A1RAB9AMAPK1 | |
| SCHEMBL6904254 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL9779996 | 0.80 | MAPT (0.56) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL8285571 | 0.80 | KMT2A (0.59) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL9779970 | 0.79 | GAA (0.53) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL1733736 | 0.79 | GRK2 (0.47) | MEN1KMT2AALDH1A1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4000609-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | Industry Foundation of Chonnam National University (KR) | 2022-05-25 | — | — | EP | disclosed |