Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | GRK3 | P35626 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 12/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490577 | 0.87 | AKR1C3 (0.60) | MEN1KMT2AAKR1C3CA12CA2 | |
| SCHEMBL15057284 | 0.87 | HPGD (0.48) | MEN1KMT2AAKR1C3 | |
| SCHEMBL7429994 | 0.86 | CASR (0.52) | MEN1KMT2AAKR1C3 | |
| SCHEMBL11283115 | 0.85 | PARP1 (0.52) | PARP14MEN1KMT2AGRK2GRK5 | |
| SCHEMBL11088028 | 0.85 | AKR1C3 (0.47) | GRK2GRK3AKR1C3CA12CA1 | |
| SCHEMBL4119738 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AAKR1C3CA12CA1 | |
| SCHEMBL24077532 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2A | |
| SCHEMBL3763507 | 0.81 | VSIR (0.53) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL12121617 | 0.81 | MAPT (0.55) | MEN1KMT2AGRK2 | |
| SCHEMBL11093055 | 0.81 | AKR1C3 (0.43) | MEN1KMT2AGRK2GRK3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576105-B2 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | JANSSEN PHARMACEUTICA, NV (BE) | 2009-08-18 | — | — | US | disclosed |
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | BAXTER ELLEN W | 2006-05-18 | — | — | US | disclosed |
| WO-2004035541-A1 | BENZYL SUBSTITUTED (PIPERIDIN-4-YL) AMINOBENZAMIDO DERIVATIVES AS DELTA-OPIOD RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-29 | — | — | WO | disclosed |
| US-20040082612-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | JANSSEN PHARMACEUTICALS N.V. (BE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | OPRD1, OPRK1, OPRM1 | PARP14 1158/4885MEN1 4868/4885KMT2A 1430/4885 |
| US-20040082612-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | OPRD1, OPRK1, OPRM1 | PARP14 1158/4885MEN1 4868/4885KMT2A 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.