Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278858 | 0.88 | SLC6A4 (0.40) | ADRB2TBXA2RLMNAMMP2MMP9 | |
| SCHEMBL11283323 | 0.85 | TBXA2R (0.36) | ADRB3TBXA2RMMP2MMP9HTR2A | |
| SCHEMBL11287791 | 0.83 | AR (0.35) | TBXA2RMMP2MMP9HTR2ASLC6A4 | |
| SCHEMBL11284068 | 0.82 | ADRB3 (0.51) | ADRB3ADRB2ADRB1LMNAKDM4E | |
| SCHEMBL11284864 | 0.80 | ADRB2 (0.37) | ADRB3ADRB2ADRB1TBXA2RLMNA | |
| Alcohol SCHEMBL11558568 | 0.78 | ADRB2 (0.41) | ADRB3ADRB2ADRB1LMNAKDM4E | |
| SCHEMBL11284063 | 0.78 | TBXA2R (0.38) | ADRB3ADRB2ADRB1TBXA2RLMNA | |
| SCHEMBL11277192 | 0.78 | MAPT (0.39) | ADRB3ADRB2ADRB1TBXA2RHTR2A | |
| SCHEMBL11526874 | 0.78 | SLC22A3 (0.56) | ADRB3ADRB2ADRB1LMNAKDM4E | |
| SCHEMBL11287411 | 0.77 | TBXA2R (0.37) | ADRB3ADRB2TBXA2RLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |