Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284864 | 0.85 | ADRB2 (0.37) | MAPK1ALDH1A1ADRB2ADRB1ADRB3 | |
| Trifluoroacetic Acid SCHEMBL11277207 | 0.82 | SLC22A3 (0.46) | MAPTMAPK1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11282523 | 0.78 | ADRB2 (0.37) | MAPTMAPK1HTR2ASLC6A4KCNH2 | |
| SCHEMBL11284062 | 0.78 | ADRB3 (0.36) | HTR2ASLC6A4KCNH2ADRB2ADRB1 | |
| SCHEMBL11526874 | 0.77 | SLC22A3 (0.56) | MAPTMAPK1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11428877 | 0.75 | ACHE (0.37) | MAPTMAPK1HTR2ASLC6A4KCNH2 | |
| SCHEMBL11284068 | 0.74 | ADRB3 (0.51) | MAPTMAPK1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL11284063 | 0.73 | TBXA2R (0.38) | ADRB2ADRB1ADRB3TBXA2RSLC22A3 | |
| SCHEMBL11282043 | 0.72 | TBXA2R (0.38) | MAPTMAPK1HTR2ASLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL11287403 | 0.70 | SLC22A3 (0.46) | MAPTMAPK1ALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |