Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773282 | 0.78 | BCAT2 (0.48) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL5180034 | 0.76 | BCAT2 (0.57) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL31521259 | 0.76 | BCAT2 (0.57) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL8908209 | 0.76 | BCAT2 (0.43) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL1034554 | 0.72 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL132986 | 0.72 | BCAT2 (1.00) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL32689453 | 0.72 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL29427545 | 0.72 | BCAT2 (1.00) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL16823343 | 0.72 | KDM4E (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL709834 | 0.72 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015776-B1 | 1,1'-BIPHENYL-2-YL ALKYLAMINE DERIVATIVES, THEIR PRODUCTION AND CARDIOVASCULAR PREPARATIONS CONTAINING SAME | ELI LILLY AND COMPANY (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4277471-A | 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| EP-0015776-A1 | 1,1'-Biphenyl-2-yl alkylamine derivatives, their production and cardiovascular preparations containing same | ELI LILLY AND COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |