Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.63 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32689453 | 1.00 | BCAT2 (0.63) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL29131061 | 0.98 | BCAT2 (0.61) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27450056 | 0.98 | BCAT2 (0.61) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31621742 | 0.98 | BCAT2 (0.61) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7151686 | 0.93 | BCAT2 (0.55) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1036499 | 0.91 | BCAT2 (0.53) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL752611 | 0.85 | F2 (0.48) | BCAT2WDR5KMT2AF2F10 | |
| SCHEMBL8328534 | 0.84 | SLC6A4 (0.53) | BCAT2WDR5KMT2AMEN1F2 | |
| SCHEMBL28513902 | 0.84 | BCAT2 (0.50) | BCAT2WDR5F2F10F7 | |
| SCHEMBL206918 | 0.84 | BCAT2 (0.46) | BCAT2WDR5KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640876-A | A kind of Multi substituted benzenes benzimidazole derivative and preparation method thereof | 华侨大学 | 2018-10-12 | — | — | CN | claimed |
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | claimed |
| US-20090317357-A1 | Methods for treating or preventing autoimmune disease using histamine h1 receptor-blocking agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-24 | — | — | US | claimed |
| WO-2004075845-A2 | METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASE USING HISTAMINE H1 RECEPTOR-BLOCKING AGENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-09-10 | — | — | WO | claimed |
| EP-1263857-A2 | CURABLE PERFLUOROELASTOMER COMPOSITION | DUPONT DOW ELASTOMERS L.L.C. (US) | 2002-12-11 | — | — | EP | claimed |
| US-6433130-B1 | POLYMERIZATION CATALYST; STABILITY | SEKISUI CHEMICAL CO., LTD. (JP) | 2002-08-13 | — | — | US | claimed |
| WO-2001059005-A2 | CURABLE PERFLUOROELASTOMER COMPOSITION | DUPONT DOW ELASTOMERS L.L.C. (US) | 2001-08-16 | — | — | WO | claimed |
| JP-52095635-A | — | — | None | — | — | JP | disclosed |
| US-20240150506-A1 | CURING AGENTS FOR FLUOROELASTOMERS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2024-05-09 | — | — | US | disclosed |
| CN-117529520-A | Fluoroelastomer compositions containing curative | 杜邦特种产品美国有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-4305096-A1 | FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS | Dupont Specialty Products USA, LLC (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |
| CN-117263869-A | Method for synthesizing N-aryl benzimidazole derivative | 郑州轻工业大学 | 2023-12-22 | — | — | CN | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0059156-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLEACETIC-ACID DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-23 | — | — | EP | disclosed |
| EP-0001965-B1 | PROCESS FOR THE PREPARATION OF FOAMED MATERIALS | BAYER AG (DE) | 1982-12-15 | — | — | EP | disclosed |
| JP-S5295635-A | NOVEL N-CYCLOHEXYL-N#-SUBSTUTUTED PHENYL-BENZAMIDINE COMPOUNDS | TOYO JOZO CO LTD | 1977-08-11 | — | — | JP | disclosed |