Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133281 | 0.80 | BCAT2 (0.44) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL10717203 | 0.79 | BCAT2 (0.52) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL8605196 | 0.76 | BCAT2 (0.41) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL8605191 | 0.76 | BCAT2 (0.41) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL11284290 | 0.76 | BCAT2 (0.57) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL11630587 | 0.76 | CA1 (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10628115 | 0.74 | CES2 (0.42) | MEN1KMT2AGPR52ALDH1A1TSHR | |
| SCHEMBL8773282 | 0.73 | BCAT2 (0.48) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL708730 | 0.72 | AKT1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5180034 | 0.72 | BCAT2 (0.57) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767791-A1 | ARYL, ALKYL, ALKENYL AND ALKYNYLMACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO. INC. (US) | 1997-04-16 | — | — | EP | disclosed |