SCHEMBL1128432

SCHEMBL1128432

CC(C)N1C=Cc2ccccc2C1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.35
HSD17B3 P37058 1/20 0.35
HRH3 Q9Y5N1 2/20 0.33
KCNH2 Q12809 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PARP1 P09874 1/20 0.33
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
NOTUM Q6P988 1/20 0.31
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL10822526 0.98 HDAC3 (0.35) HDAC3HSD17B3HRH3KCNH2MEN1
SCHEMBL5141014 0.85 HDAC3 (0.37) HDAC3HSD17B3HRH3KCNH2MEN1
SCHEMBL9809180 0.82 MEN1 (0.37) HDAC3HSD17B3KCNH2MEN1KMT2A
SCHEMBL27936399 0.77 MEN1 (0.33) HDAC3MEN1KMT2A
SCHEMBL27936286 0.77 MEN1 (0.33) HDAC3MEN1KMT2A
SCHEMBL27936293 0.77 MEN1 (0.33) HDAC3MEN1KMT2A
SCHEMBL26624307 0.75 HSD17B3 (0.30) HSD17B3
SCHEMBL26620754 0.75 HSD17B3 (0.30) HSD17B3
SCHEMBL1564351 0.74 HDAC3 (0.41) HDAC3HSD17B3KCNH2MEN1KMT2A
SCHEMBL30385312 0.74 HDAC3 (0.41) HDAC3HSD17B3KCNH2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4580855-A COOLING TO SOLIDIFY 7,7,8,8-TETRACYANOQUINODIMETHANE COMPLEX SALT SANYO ELECTRIC CO., LTD. (JP) 1986-04-08 US claimed
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS THE SCRIPPS RESEARCH INSTITUTE 2020-12-17 US disclosed
US-20200259085-A1 TREATMENT LIQUID CONTAINING IONIC COMPOUND, ORGANIC ELECTRONIC ELEMENT, AND METHOD FOR PRODUCING ORGANIC ELECTRONIC ELEMENT HITACHI CHEMICAL COMPANY, LTD. 2020-08-13 US disclosed
CN-106939074-B Treatment liquid containing ionic compound 日立化成株式会社 2020-06-16 CN disclosed
US-10665786-B2 Treatment liquid containing ionic compound, organic electronic element, and method for producing organic electronic element HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-05-26 US disclosed
US-20200143954-A1 ORGANIC ELECTRONIC MATERIAL, POLYMERIZATION INITIATOR AND THERMAL POLYMERIZATION INITIATOR, INK COMPOSITION, ORGANIC THIN FILM AND PRODUCTION METHOD FOR SAME, ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, DISPLAY ELEMENT, AND DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-05-07 US disclosed
US-10566105-B2 Method for producing charge transport film HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-02-18 US disclosed
US-20180162847-A1 PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF Epizyme, Inc. (US) 2018-06-14 US disclosed
US-9908887-B2 PRMT5 inhibitors and uses thereof Epizyme, Inc. (US) 2018-03-06 US disclosed
US-9745291-B2 PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof Epizyme, Inc. (US) 2017-08-29 US disclosed
US-4982312-A N,N-ALKYLENE-DI-3,5-LUTIDINE COMPLEXEED WITH 7,7,8,8-TETRACYANOQUINODIMETHAN THE JAPAN CARLIT CO., LTD. (JP) 1991-01-01 US disclosed
US-4943892-A METAL, DIELECTRIC FILM, MANGANESE DIOXIDE, CONDUCTIVE POLYMER MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-07-24 US disclosed
EP-0367147-A2 Charge transfer complex and solid electrolytic capacitor employing the same THE JAPAN CARLIT CO., LTD. (JP) 1990-05-09 EP disclosed
EP-0358239-A2 Solid electrolytic capacitor and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-03-14 EP disclosed
EP-0336299-A2 Solid electrolytic capacitor and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-10-11 EP disclosed
US-4828738-A ORGANIC SEMICONDUCTOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-05-09 US disclosed
US-4688153-A ELECTROLYTIC CAPACITORS THE JAPAN CARLIT CO., LTD. (JP) 1987-08-18 US disclosed
EP-0224207-A2 Charge transfer complex THE JAPAN CARLIT CO., LTD. (JP) 1987-06-03 EP disclosed
US-4590541-A SUPPRESSORS OF POLYHYDRIC ALCOHOLS TO PREVENT EVOLUTION OF TOXIC HYDROGEN CYANIDE UPON EXCESSIVE HEATING MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1986-05-20 US disclosed
US-4580855-A COOLING TO SOLIDIFY 7,7,8,8-TETRACYANOQUINODIMETHANE COMPLEX SALT SANYO ELECTRIC CO., LTD. (JP) 1986-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS RNGTT, MAX, POLRMT HDAC3 4376/4885HSD17B3 4839/4885HRH3 2414/4885
US-20180162847-A1 PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF PRMT5, PRMT1, PRMT3 HDAC3 106/4885HSD17B3 3178/4885HRH3 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.