Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371936 | 0.95 | SLC6A2 (0.46) | SLC6A2SLC6A3HTR7CES2CES1 | |
| Ethylene SCHEMBL11105901 | 0.91 | SLC6A2 (0.44) | SLC6A2SLC6A3HTR7CES2CES1 | |
| SCHEMBL13232543 | 0.79 | SLC6A2 (0.48) | SLC6A2SLC6A3ALDH1A1HPGDEPHX2 | |
| SCHEMBL7457651 | 0.78 | SMN1; SMN2 (0.47) | SLC6A2SLC6A3CES2CES1ALDH1A1 | |
| SCHEMBL27513862 | 0.78 | PDPK1 (0.55) | SLC6A2SLC6A3ALDH1A1HPGDCA1 | |
| SCHEMBL633350 | 0.76 | PGR (0.52) | SLC6A2SLC6A3CES2CES1ALDH1A1 | |
| SCHEMBL10522721 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A3HTR7CES2CES1 | |
| SCHEMBL13262327 | 0.74 | ALDH1A1 (0.49) | SLC6A2SLC6A3HTR7CES2CES1 | |
| SCHEMBL11851363 | 0.74 | HDAC1 (0.47) | ALDH1A1EPHX2NPC1RAB9ATDP1 | |
| SCHEMBL5151026 | 0.74 | CES2 (0.50) | SLC6A2SLC6A3HTR7CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329464-A | ANTIHYPERTENSIVE AGENTS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4079141-A | ANALGESICS | AMERICAN HOECHST CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |