Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533793 | 0.91 | APP (0.40) | RRM1NFE2L2KDM4ERAB9ANPC1 | |
| SCHEMBL27725980 | 0.86 | NFE2L2 (0.52) | NFE2L2KDM4ERAB9ANPC1CASP3 | |
| SCHEMBL554449 | 0.85 | RELA (0.44) | ALOX5MAPTRELACHRM1L3MBTL1 | |
| SCHEMBL554639 | 0.85 | RELA (0.44) | ALOX5MAPTRELACHRM1L3MBTL1 | |
| SCHEMBL129341 | 0.84 | RELA (0.52) | NFE2L2KDM4ERAB9ANPC1CYP1A2 | |
| SCHEMBL129342 | 0.84 | RELA (0.52) | NFE2L2KDM4ERAB9ANPC1CYP1A2 | |
| SCHEMBL31589640 | 0.84 | RELA (0.52) | NFE2L2KDM4ERAB9ANPC1CYP1A2 | |
| SCHEMBL8909951 | 0.82 | CYP2D6 (0.49) | KDM4ECYP1A2CYP2A6MAPTCHRM1 | |
| SCHEMBL8909959 | 0.82 | CYP2D6 (0.49) | KDM4ECYP1A2CYP2A6MAPTCHRM1 | |
| Dimethylamine SCHEMBL11173429 | 0.81 | RELA (0.46) | NFE2L2KDM4ERAB9APTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363859-A | ANTHRACENE CHARGE TRANSPORT COMPOUNDS | RICOH COMPANY, LTD. (JP) | 1982-12-14 | — | — | US | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |