SCHEMBL27725980

SCHEMBL27725980

Cc1ccc(C=Cc2c3ccccc3c(C=Cc3ccc(C)cc3)c3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.52
RELA Q04206 1/20 0.48
FGF23 Q9GZV9 1/20 0.47
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
KDM4E B2RXH2 3/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
PTGS2 P35354 2/20 0.45
ALOX5 P09917 1/20 0.45
PTGS1 P23219 1/20 0.45
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
CYP3A4 P08684 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26867256 0.90 CYP19A1 (0.55) NFE2L2RELAFGF23NPC1RAB9A
SCHEMBL135965 0.89 APP (0.44) NFE2L2RELAFGF23NPC1RAB9A
SCHEMBL135964 0.89 APP (0.44) NFE2L2RELAFGF23NPC1RAB9A
SCHEMBL11284875 0.86 RRM1 (0.45) NFE2L2RELAFGF23NPC1RAB9A
SCHEMBL4288335 0.83 NFE2L2 (0.54) NFE2L2RELAMEN1KMT2A
SCHEMBL4304905 0.80 NFE2L2 (0.56) NFE2L2RELAMEN1KMT2A
SCHEMBL4585865 0.80 NFE2L2 (0.61) NFE2L2RELAFGF23PTGS2ALOX5
SCHEMBL700269 0.80 NFE2L2 (0.61) NFE2L2RELAFGF23PTGS2ALOX5
SCHEMBL4585867 0.80 NFE2L2 (0.61) NFE2L2RELAFGF23PTGS2ALOX5
SCHEMBL30129708 0.80 NFE2L2 (0.56) NFE2L2RELAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101279888-A 9,10-divinyl anthracene derivate and application thereof to organic electroluminescent devices UNIV JILIN (CN) 2008-10-08 CN disclosed