SCHEMBL11285299

SCHEMBL11285299

CC(=CCN1C(=O)c2ccccc2C1=O)CBr

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
CASP3 P42574 1/20 0.46
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
DRD3 P35462 1/20 0.42
GSK3B P49841 1/20 0.40
GLS O94925 1/20 0.40
HPGD P15428 2/20 0.39
PLIN1 O60240 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
PLIN5 Q00G26 1/20 0.39
ABHD5 Q8WTS1 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21744814 1.00 ALDH1A1 (0.49) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL11285292 1.00 ALDH1A1 (0.49) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL1973157 0.85 ALDH1A1 (0.50) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL21744525 0.85 ALDH1A1 (0.50) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL1973155 0.85 ALDH1A1 (0.50) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL4017572 0.82 ALDH1A1 (0.55) ALDH1A1CASP3CA12CA9DRD3
SCHEMBL1969539 0.80 CA12 (0.51) ALDH1A1CASP3CA12CA9GSK3B
SCHEMBL1969540 0.80 CA12 (0.51) ALDH1A1CASP3CA12CA9GSK3B
SCHEMBL9330335 0.80 MAPT (0.52) ALDH1A1CASP3DRD3MAPTALOX15
SCHEMBL9330325 0.80 MAPT (0.52) ALDH1A1CASP3DRD3MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046283-A2 4-Phenoxy-2-butene derivatives and their use as plant growth regulators J.T. Baker Chemical Co. (US) 1982-02-24 EP disclosed