Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330325 | 1.00 | MAPT (0.52) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL6551817 | 0.98 | MAPT (0.54) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL3090702 | 0.98 | MAPT (0.54) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL9330371 | 0.98 | MAPT (0.54) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL6551812 | 0.98 | MAPT (0.54) | MAPTPGRHTR1AADORA3PTGS1 | |
| SCHEMBL4017572 | 0.85 | ALDH1A1 (0.55) | MAPTDRD3ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1973155 | 0.81 | ALDH1A1 (0.50) | MAPTDRD3ALDH1A1ALOX15CASP3 | |
| SCHEMBL21744525 | 0.81 | ALDH1A1 (0.50) | MAPTDRD3ALDH1A1ALOX15CASP3 | |
| SCHEMBL1973157 | 0.81 | ALDH1A1 (0.50) | MAPTDRD3ALDH1A1ALOX15CASP3 | |
| SCHEMBL21744814 | 0.80 | ALDH1A1 (0.49) | MAPTDRD3ALDH1A1ALOX15CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227036-B | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-11 | — | — | CN | disclosed |
| US-20220089521-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-3904330-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | Academy Of Military Medical Sciences (CN) | 2021-11-03 | — | — | EP | disclosed |
| CN-113227036-A | Ethylenediamine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020135569-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-07-02 | — | — | WO | disclosed |
| EP-0380669-B1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5130483-A | Antiulcer agents and enzyme inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0380669-A1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089521-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | UROD, FURIN, TMPRSS15 | MAPT 11/4885PGR 4535/4885HTR1A 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.