Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973155 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CASP3CA12CA9NPSR1 | |
| SCHEMBL21744525 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CASP3CA12CA9NPSR1 | |
| SCHEMBL11285292 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CASP3CA12CA9GLS | |
| SCHEMBL11285299 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CASP3CA12CA9GLS | |
| SCHEMBL21744814 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CASP3CA12CA9GLS | |
| SCHEMBL4017572 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CASP3CA12CA9NPSR1 | |
| SCHEMBL9330325 | 0.81 | MAPT (0.52) | ALDH1A1CASP3DRD3MAPTALOX15 | |
| SCHEMBL9330335 | 0.81 | MAPT (0.52) | ALDH1A1CASP3DRD3MAPTALOX15 | |
| SCHEMBL16623099 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CASP3CA12CA9NPSR1 | |
| SCHEMBL9330371 | 0.80 | MAPT (0.54) | ALDH1A1CASP3DRD3MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086454-A1 | Preparation of trans-zeatin intermediate | J.T. Baker Chemical Co. (US) | 1983-08-24 | — | — | EP | claimed |
| EP-2509424-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-0896063-B9 | Method for the selection of genetically transformed cells and compounds for use in the method | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| EP-0896063-B1 | Method for the selection of genetically transformed cells and compounds for use in the method | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-23 | — | — | EP | disclosed |
| EP-0601092-B2 | METHOD FOR THE SELECTION OF GENETICALLY TRANSFORMED CELLS AND COMPOUNDS FOR USE IN THE METHOD | SYNGENTA PARTICIPATIONS AG (CH) | 2006-11-15 | — | — | EP | disclosed |
| US-5994629-A | Positive selection | NOVARTIS AG (CH) | 1999-11-30 | — | — | US | disclosed |
| EP-0601092-B1 | METHOD FOR THE SELECTION OF GENETICALLY TRANSFORMED CELLS AND COMPOUNDS FOR USE IN THE METHOD | NOVARTIS AG (CH) | 1999-07-07 | — | — | EP | disclosed |
| EP-0896063-A2 | Method for the selection of genetically transformed cells and compounds for use in the method | Novartis AG (CH) | 1999-02-10 | — | — | EP | disclosed |
| US-5210077-A | Plant growth regulators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0530129-A1 | Method for the selection of genetically transformed cells and compounds for use in the method | SANDOZ LTD. (CH) | 1993-03-03 | — | — | EP | disclosed |
| EP-0086454-A1 | Preparation of trans-zeatin intermediate | J.T. Baker Chemical Co. (US) | 1983-08-24 | — | — | EP | disclosed |
| EP-0086454-A1 | Preparation of trans-zeatin intermediate | J.T. Baker Chemical Co. (US) | 1983-08-24 | — | — | EP | disclosed |