Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137914 | 0.80 | GRM5 (0.42) | F9PLAUCCR1KCNH2TSHR | |
| SCHEMBL98343 | 0.77 | HTR5A (0.50) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11345336 | 0.73 | ALDH1A1 (0.46) | F9PLAUTSHRALDH1A1HPGD | |
| SCHEMBL28629553 | 0.72 | CRBN (0.47) | TSHRALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL30114834 | 0.72 | CRBN (0.47) | TSHRALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL18513671 | 0.71 | NPC1 (0.40) | CCR1KCNH2NPC1MAPK13MAPK12 | |
| SCHEMBL11285856 | 0.71 | SMN1; SMN2 (0.46) | F9TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL12090742 | 0.71 | CYP19A1 (0.48) | CCR1KCNH2ALDH1A1HPGDKDM4E | |
| SCHEMBL11278612 | 0.68 | LMNA (0.46) | CCR1KCNH2NPC1MAPK13MAPK12 | |
| SCHEMBL8919465 | 0.68 | NPC1 (0.46) | TSHRHPGDKDM4ENPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |