SCHEMBL11285451

SCHEMBL11285451

ClCc1nc(Cl)nc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10542112 0.76
SCHEMBL14231084 0.75 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL10378513 0.75 LMNA (0.31)
SCHEMBL218726 0.73 ALDH1A1 (0.54) ALDH1A1ALOX15TSHRCYP1A2
SCHEMBL20797980 0.72 CYP1A2 (0.33) CYP1A2
SCHEMBL8733589 0.70 ALDH1A1 (0.61) ALDH1A1ALOX15TSHRCYP1A2
SCHEMBL20798172 0.69 CYP1A2 (0.32) CYP1A2
SCHEMBL7981865 0.69 ALDH1A1 (0.41) ALDH1A1ALOX15TSHR
SCHEMBL7996018 0.68
SCHEMBL9626016 0.68 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0065479-A2 Reactive dyestuffs, process for their preparation and their use in dyeing and printing materials containing hydroxyl groups or nitrogen BAYER AG (DE) 1982-11-24 EP disclosed