Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10976674 | 0.80 | KDM1A (0.54) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL21391383 | 0.79 | PPARA (0.78) | LMNACYP2C9TSHRBLMPPARA | |
| Ciprofibrate SCHEMBL8164529 | 0.79 | PPARA (1.00) | LMNACYP2C9TSHRBLMPPARA | |
| Ciprofibrate SCHEMBL26870 | 0.79 | PPARA (1.00) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL28533794 | 0.76 | KDM1A (0.52) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL11272653 | 0.76 | LMNA (0.57) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL5315412 | 0.74 | LMNA (0.67) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL9779928 | 0.74 | LMNA (0.74) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL28885355 | 0.74 | KDM1A (0.50) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL18158907 | 0.73 | MAPT (0.42) | LMNACYP2C9TSHRBLMPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043492-A2 | 1-Aryl-cyclopropane-1-carboxylic-acid esters, their preparation and their use as insecticides | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |