Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | PPARA | Q07869 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciprofibrate SCHEMBL26870 | 0.80 | PPARA (1.00) | LMNAPPARACYP2C9TSHRBLM | |
| Ciprofibrate SCHEMBL8164529 | 0.80 | PPARA (1.00) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL21391383 | 0.80 | PPARA (0.78) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL4337820 | 0.79 | MEN1 (0.63) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL9779928 | 0.78 | LMNA (0.74) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL11013173 | 0.75 | PPARA (0.69) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL4344294 | 0.75 | LMNA (0.50) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL4335866 | 0.74 | NQO1 (0.52) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL5318531 | 0.74 | LMNA (0.50) | LMNAPPARACYP2C9TSHRBLM | |
| SCHEMBL21413780 | 0.74 | LMNA (0.67) | LMNAPPARACYP2C9TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2007100161-A1 | METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-09-07 | — | — | WO | disclosed |