Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.60 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.60 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285757 | 0.83 | KCNA3 (0.58) | CHRNA7NPC1RAB9AALDH1A1KCNA3 | |
| SCHEMBL11693379 | 0.80 | CHRNA7 (0.66) | CHRNA7CHRNA10CHRNA9PPARAPPARG | |
| SCHEMBL28330356 | 0.80 | CHRNA7 (0.66) | CHRNA7CHRNA10CHRNA9PPARAPPARG | |
| SCHEMBL9224163 | 0.77 | ALDH1A1 (0.67) | CHRNA7CHRNA10CHRNA9PPARAPPARG | |
| SCHEMBL29183506 | 0.77 | TAAR1 (0.67) | CHRNA7CHRNA10CHRNA9PPARAPPARG | |
| SCHEMBL9224161 | 0.77 | ALDH1A1 (0.67) | CHRNA7CHRNA10CHRNA9PPARAPPARG | |
| SCHEMBL11836150 | 0.76 | LTA4H (0.64) | CHRNA7CHRNA10CHRNA9PPARANPC1 | |
| SCHEMBL19281444 | 0.76 | LTA4H (0.64) | CHRNA7CHRNA10CHRNA9PPARANPC1 | |
| SCHEMBL4942746 | 0.76 | LTA4H (0.64) | CHRNA7CHRNA10CHRNA9PPARANPC1 | |
| SCHEMBL1984435 | 0.76 | LTA4H (0.64) | CHRNA7CHRNA10CHRNA9PPARANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275070-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7794945-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-09-14 | — | — | US | disclosed |
| US-7556923-B1 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048427-A1 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS | DDB1, LIG3, MSH2 | CHRNA7 396/4885CHRNA10 1004/4885CHRNA9 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.