Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287934 | 0.95 | ALOX15 (0.39) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11276281 | 0.89 | ALOX15 (0.49) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11288774 | 0.85 | ALOX15 (0.44) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11288059 | 0.84 | ALOX15 (0.45) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11279194 | 0.83 | ALDH1A1 (0.40) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11277602 | 0.83 | ADRB2 (0.45) | ALOX15PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11284028 | 0.83 | TSHR (0.41) | PDE4B | |
| SCHEMBL11282096 | 0.83 | ALDH1A1 (0.40) | PDE4BADRB2 | |
| SCHEMBL11284412 | 0.82 | ALOX15 (0.45) | ALOX15ADRB2ADRB1ADRB3 | |
| SCHEMBL11291258 | 0.81 | ALOX15 (0.44) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |