SCHEMBL11286015

SCHEMBL11286015

FC(F)(F)c1ccccc1-c1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.54
AR P10275 1/20 0.53
HSD11B1 P28845 2/20 0.51
FFAR4 Q5NUL3 1/20 0.51
SLC13A5 Q86YT5 1/20 0.48
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
TRPA1 O75762 3/20 0.47
SCN9A Q15858 2/20 0.47
BACE1 P56817 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
CNR2 P34972 2/20 0.47
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
USP1 O94782 1/20 0.44
WDR48 Q8TAF3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29980535 1.00 KIF11 (0.54) KIF11ARHSD11B1FFAR4SLC13A5
SCHEMBL5523215 1.00 KIF11 (0.54) KIF11ARHSD11B1FFAR4SLC13A5
SCHEMBL24297565 0.95 AR (0.56) KIF11ARHSD11B1FFAR4SLC13A5
SCHEMBL163729 0.95 HSD11B1 (0.55) KIF11ARHSD11B1FFAR4SLC13A5
SCHEMBL15913258 0.93 AR (0.50) KIF11ARHSD11B1FFAR4SLC13A5
Benzene SCHEMBL29143034 0.93 AR (0.50) KIF11ARHSD11B1FFAR4SLC13A5
Ethyne SCHEMBL27849625 0.93 HSD11B1 (0.53) KIF11ARHSD11B1FFAR4SLC13A5
Methane SCHEMBL28022370 0.93 HSD11B1 (0.53) KIF11ARHSD11B1FFAR4SLC13A5
Water SCHEMBL7091891 0.93 AR (0.55) KIF11ARHSD11B1FFAR4SLC13A5
Water SCHEMBL27916635 0.93 AR (0.55) KIF11ARHSD11B1FFAR4SLC13A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061026-A1 Substituted-quaterphenylene polyamides POLAROID CORPORATION (US) 1982-09-29 EP disclosed