SCHEMBL11286127

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	14/20	0.58

▸	OPRD1	P41143	3/20	0.56

▸	OPRM1	P35372	2/20	0.56

▸	CCKBR	P32239	3/20	0.56

▸	CCKAR	P32238	1/20	0.56

▸	IL1RN	P18510	1/20	0.54

▸	ERAP2	Q6P179	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11286119	1.00	KISS1R (0.58)	KISS1ROPRD1OPRM1CCKBRCCKAR
SCHEMBL30906491	0.85	GLP1R (0.59)	KISS1R
SCHEMBL30512689	0.84	KISS1R (0.60)	KISS1R
SCHEMBL30307612	0.84	OPRM1 (0.67)	KISS1ROPRD1OPRM1CCKBRCCKAR
SCHEMBL30349481	0.83	ERAP2 (0.65)	KISS1ROPRD1CCKBRCCKARIL1RN
SCHEMBL30542889	0.83	CCKBR (0.61)	OPRD1OPRM1CCKBRCCKARIL1RN
SCHEMBL11659149	0.83	CCKBR (0.68)	KISS1ROPRD1OPRM1CCKBR
SCHEMBL11666813	0.83	CCKBR (0.68)	KISS1ROPRD1OPRM1CCKBR
SCHEMBL30051762	0.82	ACE (0.56)	OPRD1OPRM1
SCHEMBL31462103	0.82	GLP1R (0.58)	KISS1RERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4351828-A	N-Substituted cyclopeptide derivatives	AMERICAN HOME PRODUCTS CORPORATION (US)	1982-09-28	—	—	US	disclosed
US-4237045-A	N-substituted cyclopeptide derivatives and preparation thereof	AMERICAN HOME PRODUCTS CORPORATION (US)	1980-12-02	—	—	US	disclosed