Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791643 | 0.84 | HTR3A (0.62) | KDM4EPIK3CDMAPTALDH1A1GAA | |
| SCHEMBL11792670 | 0.84 | HTR2C (0.52) | HTR2CKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL23107849 | 0.82 | ALOX15 (0.49) | HTR2CKDM4EHTTPIK3CDMAPT | |
| SCHEMBL11789146 | 0.82 | PRKDC (0.50) | KDM4EHTTPIK3CDMAPTALDH1A1 | |
| SCHEMBL11791601 | 0.82 | HTR2C (0.50) | HTR2CKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL754236 | 0.79 | KDM4E (0.55) | KDM4EHTTPIK3CDMAPTALDH1A1 | |
| SCHEMBL17506310 | 0.76 | KDM4E (0.55) | KDM4EHTTMAPTALDH1A1GAA | |
| SCHEMBL12215244 | 0.76 | HTR2C (0.59) | HTR2CKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL17531170 | 0.76 | ALDH1A1 (0.62) | KDM4EHTTMAPTALDH1A1GAA | |
| SCHEMBL1486973 | 0.76 | HTR2C (0.59) | HTR2CKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324894-A | NARCOSIS POTENTIATING | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-04-13 | — | — | US | disclosed |
| US-3975524-A | ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |