Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280815 | 0.83 | GSK3B (0.33) | GSK3BKDM4ECYP3A4CYP2C9PTPRB | |
| SCHEMBL2824127 | 0.76 | KDM4E (0.53) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| Water SCHEMBL11160916 | 0.74 | KDM4E (0.52) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11283559 | 0.74 | KDM4E (0.34) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11184996 | 0.74 | SCN9A (0.38) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11165939 | 0.73 | EGLN1 (0.36) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11283253 | 0.71 | KDM4E (0.32) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11276440 | 0.71 | KDM4E (0.32) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11161094 | 0.69 | ALOX15 (0.44) | KDM4ECYP3A4CYP2C9PTPRBHSD17B10 | |
| SCHEMBL11389233 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013905-B1 | 4,5-DICHLORO-IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS HERBICIDES | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0013905-A1 | 4,5-Dichloro-imidazole derivatives, their preparation and their application as herbicides | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |