Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287005 | 0.88 | HDAC1 (0.45) | MAPTTSHRMAPK1HDAC1MEN1 | |
| SCHEMBL11288356 | 0.84 | MAPT (0.48) | MAPTLMNAMAPK1HTTADORA1 | |
| SCHEMBL11292931 | 0.84 | MAPT (0.51) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL29611914 | 0.81 | KEAP1 (0.67) | MAPTGAAPOLBLMNATSHR | |
| SCHEMBL2473546 | 0.81 | KEAP1 (0.67) | MAPTGAAPOLBLMNATSHR | |
| SCHEMBL11294333 | 0.80 | MAPT (0.49) | MAPTGAAPOLBLMNATSHR | |
| SCHEMBL11287081 | 0.80 | NPC1 (0.50) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL11296456 | 0.80 | ALDH1A1 (0.43) | MAPTGAAPOLBLMNAHTT | |
| SCHEMBL24354139 | 0.80 | BCL2 (0.50) | MAPTGAAPOLBLMNAMAPK1 | |
| SCHEMBL11293046 | 0.80 | MAPT (0.53) | MAPTGAAPOLBHTTBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |