Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 7/20 | 0.50 |
| ▸ | GSK3A | P49840 | 6/20 | 0.50 |
| ▸ | AURKA | O14965 | 5/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408101 | 0.84 | GSK3B (0.57) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11179027 | 0.83 | GSK3B (0.47) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11348508 | 0.81 | GSK3B (0.72) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11287202 | 0.81 | MEN1 (0.53) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11291261 | 0.81 | MAPT (0.53) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL3586236 | 0.79 | GSK3B (0.43) | MEN1MAPTKMT2AGSK3BAURKA | |
| SCHEMBL11002558 | 0.79 | RAB9A (0.42) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11193854 | 0.77 | PTK2B (0.48) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL11187199 | 0.76 | MEN1 (0.47) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL12705395 | 0.69 | GSK3B (0.74) | MEN1CYP1A2CYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051773-A1 | Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |