Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894571 | 0.88 | ALDH1A1 (0.68) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11284116 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL3056066 | 0.83 | CDC7 (0.65) | ALDH1A1NPSR1SMN1; SMN2CDC7DBF4 | |
| SCHEMBL27583074 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAAHTTNPSR1SMN1; SMN2 | |
| SCHEMBL11278098 | 0.81 | LMNA (0.64) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL3893108 | 0.77 | ALDH1A1 (0.71) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11279454 | 0.77 | ALDH1A1 (0.59) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11286855 | 0.76 | SMN1; SMN2 (0.54) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11753179 | 0.76 | ALDH1A1 (0.60) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11288991 | 0.75 | ALDH1A1 (0.57) | ALDH1A1GAAHTTNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |