Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785502 | 0.82 | ADORA2A (0.32) | NR1H3ADORA2A | |
| SCHEMBL12519609 | 0.76 | NR1H3 (0.42) | NR1H3KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL10284719 | 0.73 | NR1H3 (0.40) | NR1H3KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL19286101 | 0.69 | SLC9A1 (0.38) | NR1H3KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL17508789 | 0.68 | KMT2A (0.41) | KMT2AMEN1CYP1A2MAPTSLC9A1 | |
| SCHEMBL21960147 | 0.67 | ADORA2A (0.33) | ADORA2A | |
| SCHEMBL8109107 | 0.67 | ADORA3 (0.41) | NR1H3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4223371 | 0.62 | TOP2A (0.39) | NR1H3KMT2AMPOALDH1A1POLB | |
| SCHEMBL11858090 | 0.60 | ESR1 (0.38) | NR1H3KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL12344045 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065217-A2 | 5-Haloalkyl-1,2,4-triazole and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0065216-A1 | Pesticidal S-(1,2,4-triazol-5-yl-methyl)-(di)-thiophosph(on)ates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |