Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955250 | 0.91 | TBXAS1 (0.55) | TBXAS1GPR35TAAR1ROCK1HTR1A | |
| SCHEMBL10953653 | 0.87 | ROCK1 (0.45) | TBXAS1TAAR1ROCK1 | |
| SCHEMBL10952018 | 0.81 | TBXAS1 (0.53) | TBXAS1GPR35TAAR1RXFP1PKM | |
| SCHEMBL10953013 | 0.78 | TBXAS1 (0.42) | TBXAS1TAAR1ROCK1HTR1ANPSR1 | |
| SCHEMBL149468 | 0.78 | TBXAS1 (0.54) | TBXAS1TAAR1ROCK1HTR1A | |
| Hydrochloric Acid SCHEMBL10853856 | 0.77 | TBXAS1 (0.53) | TBXAS1TAAR1ROCK1HTR1A | |
| SCHEMBL9613211 | 0.76 | TBXAS1 (0.60) | TBXAS1GPR35RXFP1PKMNPSR1 | |
| SCHEMBL10948748 | 0.76 | TBXAS1 (0.60) | TBXAS1GPR35ROCK1RXFP1PKM | |
| SCHEMBL9757026 | 0.75 | TBXAS1 (0.58) | TBXAS1GPR35ROCK1RXFP1PKM | |
| SCHEMBL11168704 | 0.71 | TBXAS1 (0.41) | TBXAS1TAAR1ROCK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050957-A1 | Heterocyclic thromboxane synthetase inhibitors, processes for their preparation, and pharmaceutical compositions containing them | Pfizer Limited (GB) | 1982-05-05 | — | — | EP | disclosed |