SCHEMBL11287677

SCHEMBL11287677

COc1ccc(C=NN(c2ccccc2)c2ccccc2)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 2/20 0.49
EIF4H Q15056 1/20 0.49
MAPT P10636 6/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
GCGR P47871 3/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
LMNA P02545 1/20 0.44
GAA P10253 2/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
IMPDH2 P12268 1/20 0.41
IMPDH1 P20839 1/20 0.41
CHAT P28329 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702914 0.87 MAPT (0.65) MEN1KMT2APOLBMAPTTDP1
SCHEMBL131533 0.81 MAPT (0.60) MEN1KMT2APOLBMAPTTDP1
SCHEMBL2650258 0.79 IDO1 (0.52) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL6415092 0.77 MAPT (0.51) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL11286291 0.77 HPGD (0.62) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL22203786 0.77 MAPT (0.56) MEN1KMT2APOLBEIF4HMAPT
SCHEMBL13655512 0.75 SLC16A3 (0.48) MEN1KMT2APOLBEIF4HMAPT
SCHEMBL8181026 0.73 MAPT (0.68) MEN1KMT2APOLBEIF4HMAPT
SCHEMBL8181030 0.73 MAPT (0.68) MEN1KMT2APOLBEIF4HMAPT
SCHEMBL7915395 0.73 MAPT (0.63) MEN1KMT2AMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338388-A Electrophotographic element with a phenyhydrazone charge transport layer RICOH COMPANY, LIMITED (JP) 1982-07-06 US claimed
US-4338388-A Electrophotographic element with a phenyhydrazone charge transport layer RICOH COMPANY, LIMITED (JP) 1982-07-06 US disclosed