SCHEMBL1702914

SCHEMBL1702914

COc1ccc(C=NN(C)c2ccccc2)c2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.65
MEN1 O00255 6/20 0.65
KMT2A Q03164 6/20 0.65
TDP1 Q9NUW8 3/20 0.65
SMN1; SMN2 Q16637 5/20 0.64
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
ALDH1A1 P00352 3/20 0.64
LMNA P02545 4/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
ALOX12 P18054 2/20 0.52
GCGR P47871 2/20 0.47
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
CAPN1 P07384 1/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11287677 0.87 MEN1 (0.51) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL131533 0.80 MAPT (0.60) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL11285640 0.77 HPGD (0.61) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL2921336 0.77 ALDH1A1 (0.55) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL2921333 0.77 ALDH1A1 (0.55) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL6415092 0.76 MAPT (0.51) MAPTMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1702594 0.75 MEN1 (0.51) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL28045461 0.75 MEN1 (0.51) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL28045554 0.75 MEN1 (0.80) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL2650258 0.74 IDO1 (0.52) MAPTMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-4338388-A Electrophotographic element with a phenyhydrazone charge transport layer RICOH COMPANY, LIMITED (JP) 1982-07-06 US claimed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-20100167191-A1 Electrophotographic Photoreceptor Having a Spectral Marker and Electrophotographic Printer Using the Same BANK TRUST COMPANY, NATIONAL ASSOCIATION 2010-07-01 US disclosed
US-7648811-B2 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION (US) 2010-01-19 US disclosed
EP-1456716-B1 CHARGE TRANSPORT LAYERS AND/OR CHARGE GENERATION LAYERS COMPRISING UNSATURATED ALIPHATIC HYDROCARBONS AND PHOTOCONDUCTORS INCLUDING THE SAME LEXMARK INT INC (US) 2008-09-10 EP disclosed
US-7396895-B2 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION (US) 2008-07-08 US disclosed
US-20080118853-A1 BRANCHED POLYARYLENE ETHERS AND PROCESSES FOR THE PREPARATION THEREOF XEROX CORPORATION (US) 2008-05-22 US disclosed
EP-1430362-A4 PHOTOCONDUCTORS COMPRISING CYCLIC CARBONATE POLYMERS LEXMARK INT INC (US) 2007-03-21 EP disclosed
US-20060171870-A1 PROCESS OF MAKING HYDROPHOBIC METAL OXIDE NANOPARTICLES XEROX CORPORATION (US) 2006-08-03 US disclosed
US-4880715-A Imaging system XEROX CORPORATION (US) 1989-11-14 US disclosed
US-4853307-A Imaging member containing a copolymer of styrene and ethyl acrylate XEROX CORPORATION (US) 1989-08-01 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4338388-A Electrophotographic element with a phenyhydrazone charge transport layer RICOH COMPANY, LIMITED (JP) 1982-07-06 US disclosed
US-4332948-A CHARGE TRANSPORT COMPOUNDS FOR USE IN PHOTOCONDUCTORS RICOH COMPANY, LTD. (JP) 1982-06-01 US disclosed